research

About our research activities

BIOMIG is currently involved in several research activities, which are briefly described below. Please contact us if you have any questions regarding our research.

Medical Image Processing
Development of algorithms for the enhancement, interpolation, segmentation of medical images from various medical imaging (X-ray, CT, MRI, fMRI, PET, SPECT, ultrasound). Development of algorithms based on Mathematical Morphology, fractal theory, wavelets, texture analysis, and object-oriented techniques for the digital processing of 1D, 2D and 3D medical data.

Automatic Registration and Fusion of Multidimensional Medical Data
Techniques for the automatic registration and fusion of various medical data from different imaging modalities (CT, MRI, PET, SPECT, portal images, fundus camera). Development of various algorithms for the semi-automatic registration of portal images, the automatic surface-based registration, the automatic volume-based registration and the automatic elastic-based registration. Development of fusion techniques based on mathematical morphology, logical operations, pseudo-coloring and classification techniques. Development of integrated systems for the registration and fusion of various medical data and installation on real clinical environment.

Optimization Techniques and Application to Bioinformatics
Algorithms for the optimal solution of problems in the field of bioinformatics such as registration of medical data, classification of biosignals, etc using various optimization techniques. Development and implementation of local and global optimization techniques such as Downhill Simplex, Powell Method, Simulated Annealing, and Genetics Algorithms.

Neuroimaging Applications
Development of algorithms for identifying activated brain regions, both in resting and event related states. Moreover the particular research area is concerned with the application of graphs theory for examining the deviations between healthy subjects and clinical cases (related to various conditions, such as schizophrenia, epilepsy, etc).

Digital Biosignal Processing
Algorithms of processing various biosignals in order to identify features that describe the signals. Processing of EEG (Evoked Potentials) and ECG, using multivariate autoregressive models and fractal theory.

Visualization of Medical Data
Algorithms and tools for the visualization of multidimensional medical data from different medical image modalities. Development o various algorithms for the 3D and 4D visualization of medical data based on a modification of the Marching Cubes algorithm, the Self Organizing Maps and Growing Cells Structure.

Development of Decision Support Systems
Medical image processing techniques in conjunction with neural networks for the classification of biosignals and images and the support of the diagnosis in a clinical environment. Decision support systems based on neural networks, fuzzy logic and genetics algorithms.

Sensor Data Acquisition
Research on the application of commercial sensoring devices to biomedicine. In particular, the usage of the Kinect sensor was evaluated, which is capable of modelling the surface of examined anatomical regions (such as the human back).

Medical Information Systems
Electronic patient record. Data archiving in DICOM 3.0 format and medical data transmission using compression algorithms. Telematics application with various hospital sides. Management Information System for the reengineering of the biomedical-equipment procurement process. Web-based system for the archiving and processing of gynecological data.

Telemedicine Applications
Developed an integrated system for the acquisition and transmission of medical data between distant medical units. Recently, such a system has been installed in a Healthcare Unit in the island of Samothraki (Greece), allowing the transmission of 1D (e.g. ECG, EEG) and 2D (x-ray images) medical data to the Hospital ofAlexandroupoli (Greece). Furthermore, a pilot application for the transmission of medical data, using the WEB is being under development between the Aretaieio Hospital(Athens), the Aiginiteio Hospital (Athens) and the Metropolitan Hospital of Offenbach (Germany).

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